Abstract: Circadian clocks organize an organism's daily behavior and physiology on a 24-hour time scale. These 24-hour rhythms are pervasive at all levels of organization, from complex behavior to organ specific function down to the scale of autonomous cellular oscillations. The timing in mammals is organized hierarchically, with a master pacemaker in the suprachiasmatic nuclei (SCN) controlling subordinate central and peripheral clocks making up the circadian system. This system is tuned to the environment via light and food. Derailment of tuning of the circadian system favours the development of disease such as depression and obesity. I will present evidence that clock genes are involved in the modulation mood related behavior in mice with light as an effector on this regulation.
The circadian clock and its impact on health and disease by Urs Albrecht, Ph.D.
Friday, October 30, 2020
12:00 PM – 1:00 PM